Table 2 Comparison of personal characteristics, spirometric values and carotid intima media diameter thickness degrees between groups with normal and thickened carotid intima media diameter in patients with COPD. * shows statistical significance (p <0,05)
Measurements, Values, Markers | COPD patients with normal CIMT (n=16) | Patients with a diagnosis of COPD with thickened Carotid intima-media (n=54) | Test-p value |
|---|---|---|---|
Carotid Intima-Media Thickness (CCA) /mm | 0.6594mm ± 0.75 (Mean) | 0.9370 mm ± 0.12 (Mean) | Mann Whitney U Testi=0 |
Mean ± SD , Median | 0.7mm (Median) | 0.9mm (Median) | p<0.001* |
Carotid Bulb Thickness /mm | 0.8969 mm ± 0.17 (Mean) | 1.09 mm± 0.10 (Mean) | Mann Whitney U Testi=137 |
Mean ± SD | 0.9mm (Median) | 1.1 mm (Median) | p<0.001* |
Age/Year | 56.87± 8.56 (Mean) | 63.11± 8.27 (Mean) | T-Test=-2.62 |
Mean ± SD | 57.00 (Median) | 65.00 (Median) | p=0.01* |
BMI:Kg/m2 | 27.36± 4.85 (Mean) | 26.02± 5.12 (Mean) | T-Test=0.932 |
Mean ± SD | 27.04 (Median) | 25.91 (Median) | p=0.35 |
Non-smoker | 1 (6.25%) | 5 (9.25%) | Chi square x2 (Fisher Exact)=0.141 |
Smoker | 15 (93.75) | 49 (90.75%) | OR=0.65 |
p=0.7 | |||
Smoking ( Package/year) | No=15 | No=49 | T-Test=-0.359 |
Mean ± SD | 35.2 ± 8.69 (Mean) | 36.24± 10.16 (Mean) | p=0.72 |
35.00 (Median) | 35.00 (Median) | ||
COPD duration/year | 13.06 ± 3.94 (Mean) | 15.70± 6.06 (Mean) | Mann Whitney U Testi=197.5 |
Mean± SD, Median | 13.5 (Median) | 15.00 (Median) | p=0.197 |
Hypoxemia: | Â | Â | Chi square x2 (Fisher Exact)=8.99 |
 No | 6 (37.5%) | 4 (7.5%) | OR=7.5 |
 Yes | 10 (62.5%) | 50 (92.5%) | p=0.003* |
PaO2 mmHg | 68.50 ± 12.7 (Mean) | 57.53± 8.47 (Mean) | Mann Whitney U Testi=161 |
Mean ± SD, Median | 64.6 (Median) | 56.25 (Median) | p<0.001* |
Hypercapnia : | Â | Â | Chi square x2 (Fisher Exact)=5.86 |
 No | 14 (87.5%) | 29 (53.7%) | OR=6.0 |
 Yes | 2 (12.5%) | 25 (46.3%) | p=0.015* |
PaC02 mmHg | 38.91 ± 4.80 (Mean) | 44.39± 7.63 (Mean) | Mann Whitney U Testi=225 |
Mean ± SD, Median | 35.70 (Median) | 42.70 (Median) | P=0.04* |
COPD Prevalence (degree) | |||
 Mild-Moderate | 9 (56.25%) | 18 (33.4%) | Chi square x2 (Fisher Exact)=2.697 |
 Severe-Very Severe | 7 (43.75%) | 36 (66.6%) | OR=2.5 |
Mean ± SD, Median |  |  | p=0.101 |
Fev1% | 56.0 ± 9.4 (Mean) | 44.92 ± 14.3 (Mean) | Mann Whitney U Testi=342 |
Mean ± SD, Median | 57.5 (Median) | 45.0 (Median) | p<0.001* |
FEV1/FVC | 56.87± 8.75 (Mean) | 57.09± 8.56 (Mean) | T-Test=-0.89 |
Mean ± SD, Median | 58.0 (Median) | 58.00 (Median) | p=0.92 |
FVC% | 66.81± 13.59 (Mean) | 57.40± 13.43 (Mean) | T-Test=2.45 |
Mean ± SD | 68.5 (Median) | 55.5 (Median) | p=0.017* |
FEF 25-75% | 47.81 ± 19.27 (Mean) | 34.77± 14.96 (Mean) | T-Test=2.86 |
Mean± SD | 49.5 (Median) | 35.5 (Median) | p=0.006* |