PREp and POEn (Normal, n = 96) | PREn and POEn (PRE reversed, n = 5) | PREp and POEp (POE reversed, n = 31) | PREn and POEp (Totally reversed, n = 18) | p-value | |
---|---|---|---|---|---|
Age, years | 46.7 ± 15.4 | 53 ± 17.9 | 57.4 ± 6.92 | 58.9 ± 9.6 | < 0.001#¶ |
Sex, (female), n(%) | 29 | 2 | 12 | 6 | 0.671 |
HFpEF/HFrEF/ Normal/Control, n(%) | 28/6/39/23 | 4/0/1/0 | 17/12/1/1 | 3/13/1/0 | < 0.001 |
NYHA (I/II/III/IV), n(%) | 3/24/6/1 | 0/2/2/0 | 3/16/9/0 | 0/7/9/0 | 0.015 |
NYHA (mean ± SD) | 1.6 ± 1 | 2 ± 1.2 | 2.2 ± 0.6 | 2.6 ± 0.5 | 0.001#¶ |
E (cm/s) | 74.3 ± 19.1 | 95.4 ± 25.9 | 80.6 ± 23.2 | 97.5 ± 30.7 | 0.001¶ |
A (cm/s) | 71.9 ± 22.7 | 68.3 ± 17.5 | 85.8 ± 25.1 | 62.1 ± 27.3 | 0.01#€ |
EDV (ml) | 98.1 ± 24.6 | 113.7 ± 29.7 | 115.7 ± 37.57 | 158.5 ± 67.1 | < 0.001¶$€ |
ESV (ml) | 36.8 ± 18.6 | 36.4 ± 3.5 | 57.4 ± 36.4 | 98 ± 66.7 | < 0.001¶$€ |
EF (%) | 62.8 ± 8.7 | 67 ± 4.9 | 56.4 ± 14 | 44.1 ± 14.9 | < 0.001#¶$€ |
e'-mean (cm/s) | 9.8 ± 3.1 | 8.5 ± 4.1 | 7 ± 1.9 | 6 ± 1.9 | < 0.001#¶ |
S’-mean (cm/s) | 8.3 ± 1.8 | 8.6 ± 1.8 | 7.3 ± 1.9 | 5.8 ± 1.15 | < 0.001¶$ |
E/A | 1.1 ± 0.4 | 1.53 ± 0.73 | 0.98 ± 0.4 | 1.7 ± 0.87 | < 0.001¶€ |
E/e' | 7.9 ± 2.4 | 12.8 ± 5.4 | 12.2 ± 3.7 | 17.1 ± 5.3 | < 0.001#¶€ |
PREp (mean), (cm/s) | 6.9 ± 1.9 | 4.4 ± 0.97 | 5.9 ± 1.9 | 3.3 ± 1.1 | < 0.001*#¶€ |
PREn (mean), (cm/s) | 3.1 ± 0.9 | 4.6 ± 1.1 | 3.7 ± 1.3 | 3.8 ± 1.4 | < 0.001*#¶ |
POEn (mean), (cm/s) | 3.8 ± 1.1 | 3.2 ± 0.6 | 2.6 ± 0.9 | 2.2 ± 0.6 | < 0.001#¶ |
POEp (mean), (cm/s) | 2.3 ± 0.87 | 1.9 ± 0.5 | 2.97 ± 0.82 | 3.3 ± 0.9 | < 0.001#¶‡$€ |
PREp /PREn (PRE-P/N ratio) | 2.4 ± 0.97 | 0.98 ± 0.2 | 1.64 ± 0.56 | 0.9 ± 0.17 | < 0.001*#¶€ |
POEn/POEp (POE-N/P ratio) | 2.1 ± 1.1 | 1.7 ± 0.5 | 0.87 ± 0.19 | 0.68 ± 0.21 | < 0.001#¶ |
PREp-mean/S’-mean | 0.87 ± 0.3 | 0.5 ± 0.1 | 0.8 ± 0.2 | 0.61 ± 0.17 | < 0.001*¶ |
QRS duration, ms (**) | 79.5 ± 19.7 | 73.6 ± 3.1 | 87.4 ± 23.4 | 98.4 ± 23.2 | 0.028*# |
LBBB, n(%)(**) | 2(6%) | 0(0%) | 3(10%) | 3(18%) | 0.519 |
RBBB, n(%)(**) | 1(3%) | 0(0%) | 2(7%) | 0(0%) | 0.626 |
IVCD, n(%)(**) | 0(0%) | 0(0%) | 1(3%) | 3(18%) | 0.041 |