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Table 2 Comparison of study subjects based on PRE-POE concordance

From: Tissue Doppler derived biphasic velocities during the pre and post-ejection phases: patterns, concordance and hemodynamic significance in health and disease

 

PREp and POEn (Normal, n = 96)

PREn and POEn (PRE reversed, n = 5)

PREp and POEp (POE reversed, n = 31)

PREn and POEp (Totally reversed, n = 18)

p-value

Age, years

46.7 ± 15.4

53 ± 17.9

57.4 ± 6.92

58.9 ± 9.6

 < 0.001

Sex, (female), n(%)

29

2

12

6

0.671

HFpEF/HFrEF/ Normal/Control, n(%)

28/6/39/23

4/0/1/0

17/12/1/1

3/13/1/0

 < 0.001

NYHA (I/II/III/IV), n(%)

3/24/6/1

0/2/2/0

3/16/9/0

0/7/9/0

0.015

NYHA (mean ± SD)

1.6 ± 1

2 ± 1.2

2.2 ± 0.6

2.6 ± 0.5

0.001

E (cm/s)

74.3 ± 19.1

95.4 ± 25.9

80.6 ± 23.2

97.5 ± 30.7

0.001

A (cm/s)

71.9 ± 22.7

68.3 ± 17.5

85.8 ± 25.1

62.1 ± 27.3

0.01#€

EDV (ml)

98.1 ± 24.6

113.7 ± 29.7

115.7 ± 37.57

158.5 ± 67.1

 < 0.001¶$€

ESV (ml)

36.8 ± 18.6

36.4 ± 3.5

57.4 ± 36.4

98 ± 66.7

 < 0.001¶$€

EF (%)

62.8 ± 8.7

67 ± 4.9

56.4 ± 14

44.1 ± 14.9

 < 0.001#¶$€

e'-mean (cm/s)

9.8 ± 3.1

8.5 ± 4.1

7 ± 1.9

6 ± 1.9

 < 0.001

S’-mean (cm/s)

8.3 ± 1.8

8.6 ± 1.8

7.3 ± 1.9

5.8 ± 1.15

 < 0.001¶$

E/A

1.1 ± 0.4

1.53 ± 0.73

0.98 ± 0.4

1.7 ± 0.87

 < 0.001¶€

E/e'

7.9 ± 2.4

12.8 ± 5.4

12.2 ± 3.7

17.1 ± 5.3

 < 0.001#¶€

PREp (mean), (cm/s)

6.9 ± 1.9

4.4 ± 0.97

5.9 ± 1.9

3.3 ± 1.1

 < 0.001*#¶€

PREn (mean), (cm/s)

3.1 ± 0.9

4.6 ± 1.1

3.7 ± 1.3

3.8 ± 1.4

 < 0.001*#¶

POEn (mean), (cm/s)

3.8 ± 1.1

3.2 ± 0.6

2.6 ± 0.9

2.2 ± 0.6

 < 0.001

POEp (mean), (cm/s)

2.3 ± 0.87

1.9 ± 0.5

2.97 ± 0.82

3.3 ± 0.9

 < 0.001#¶‡$€

PREp /PREn (PRE-P/N ratio)

2.4 ± 0.97

0.98 ± 0.2

1.64 ± 0.56

0.9 ± 0.17

 < 0.001*#¶€

POEn/POEp (POE-N/P ratio)

2.1 ± 1.1

1.7 ± 0.5

0.87 ± 0.19

0.68 ± 0.21

 < 0.001

PREp-mean/S’-mean

0.87 ± 0.3

0.5 ± 0.1

0.8 ± 0.2

0.61 ± 0.17

 < 0.001

QRS duration, ms (**)

79.5 ± 19.7

73.6 ± 3.1

87.4 ± 23.4

98.4 ± 23.2

0.028*#

LBBB, n(%)(**)

2(6%)

0(0%)

3(10%)

3(18%)

0.519

RBBB, n(%)(**)

1(3%)

0(0%)

2(7%)

0(0%)

0.626

IVCD, n(%)(**)

0(0%)

0(0%)

1(3%)

3(18%)

0.041

  1. * p < 0.05 between Normal and IC reversed
  2. # P < 0.05 Normal and IR reversed
  3. p < 0.05 between Normal and totally reversed
  4. p < 0.05 between IC reversed and IR reversed
  5. $ p < 0.05 between IC reversed and totally reversed
  6. p < 0.05 between IR reversed and totally reversed
  7. (**) calculated from patients with heart failure
  8. PREp positive pre-ejection, PREn negative pre-ejection, POEn negative post-ejection, POEp positive post-ejection LBBB left bundle branch block, RBBB right bundle branch block, IVCD intra-ventricular consuction delay